Boldo and boldine (an alkaloid present in boldo) extracts are known to exhibit choleretic properties (stimulating bile flow). Boldo has been shown to exert anti-inflammatory and antipyretic (anti-fever) effects. BoldinE is an effective inhibitor or prostaglandin synthesis, part of the inflammatory process. Boldo has been shown to possess cytoprotective (cell protective) and antioxidant properties.