About Allantoin Skin-softening (keratolytic), cell-proliferating healing agent, abrasive and astringent agent. Mechanism of Action of Allantoin Allantoin works by slowing bacterial growth and loosing and softening scales and crust.The keratolytic effect and abrasive and astringent properties of Allantoin are used in skin softening cosmetic preparations. Allantoin is a moisturizing, soothing, healing, anti-irritating, keratolytic and non-toxic agent. Allantoin is a cell-proliferating healing agent which stimulates healthy tissue formation. It removes necrotic and scaling tissue