About Dequalinium chloride Substituted benzimidazole , A quaternary ammonium compound, Antimicrobial agent,antiseptic , disinfectant, topical bacteriostat. Mechanism of Action of Dequalinium chloride Dequalinium chloride is an antiseptic which acts against microorganisms associated with mouth and throat infections including bacteria, and fungi. It directly acts on the area of infection and also lubricates and soothes the painful area, which helps relieve the soreness and discomfort of mouth and throat infections.