About Chymotrypsin A Proteolytic enzyme, Antiinflammatory Mechanism of Action of Chymotrypsin Chymotrypsin is a serine endopeptidase that preferentially cleaves peptide bonds on the carboxyl side of amino acids with bulky hydrophobic residues, particularly tyrosine, tryptophan, phenylalanine and leucine Indications for Chymotrypsin 1.Enzymatic zonulysis for intracapsular lens extraction 2.Edema 3.Inflammation