About Diloxanide Furoate Dichloroacetamide derivative, anti-protozoal, Luminal amebicides. Mechanism of Action of Diloxanide Furoate Diloxanide Furoate is a dicloroacetamide derivative which acts as a luminal amoebicide. It exerts its action by directly killing the trophozoites responsible for production of cysts. Indications for Diloxanide Furoate 1. Mild intestinal Amoebiasis, 2. Asymptomatic cyst passers of Entamoeba histolitica