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- Cotril fort 800mg
Cotril fort 800mg
- Scientific Name: Sulphamethoxazole 800mg.+Trimethoprim 160mg.
- Drag Period: every 8 hours after meals
- Type: Tablets
- Producing Company: Nasr
Medicine Description
Indication For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections. Mechanism of action Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.
Price: 13.43 SAR.
- Shipping to Gulf Countries
Medicine Description
Indication For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections. Mechanism of action Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.
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